Description
NC Membership Directory
 Research in the Nuclear Control Program focuses on fundamental processes in the cell nucleus that regulate the cell's biological function and go awry in the cancer cell. Researchers in the Nuclear Control Program study a variety of basic processes, including DNA replication, recombination, and repair; genetics and epigenetics; transcriptional regulation, RNA metabolism, and the role of these processes in cell growth; and division, metabolism, and oncogenic transformation. Program members use multiple model systems such as yeast, C. elegans, Drosophila, zebrafish, mouse, and patient-derived cell lines.
The Nuclear Control Program facilitates individual and cooperative research projects of representatives from many academic units on campus. It provides forums to encourage the translation of these basic research projects to more cancer-focused investigations through coordination with disease-based programs of the Cancer Center Support Grant.
The Nuclear Control of Cell Growth and Differentiation Program currently receives approximately $10.1 million per year of direct research support from the National Institutes of Health, the American Cancer Society, the National Science Foundation, and other funding agencies, with 13% coming from the National Cancer Institute. Cancer-focused articles published between 2003-2009 total 220, of which 14% are inter-programmatic and 9% are intra-programmatic publications. |
Barbara J. Graves, PhD
Co-Leader |
Stephen L. Lessnick, MD, PhD
Co-Leader |
HCI, Room 4380
(801) 581-7308
(801) 585-1980 FAX
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HCI, Room 4242
(801) 585-9268
(801) 585-6410 FAX
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