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DON AYER, PhD
Lab Head
don.ayer@hci.utah.edu
Don received his Bachelors of Science degree in Cellular and Molecular
Biology from the University of Michigan in 1983. He then moved west and,
under the mentorship of Dr. Bill Dynan, received his PhD in Biochemistry
in 1989 from the University of Colorado, Boulder. Still moving west, he
joined the lab of Dr. Bob Eisenman at the Fred Hutchinson Cancer Research
Center in Seattle. There he identified the first member of the Mad family
of transcriptional repressors and identified mSin3A as a Mad-dependent
transcriptional corepressor. Don moved back east in 1995 when he was recruited
to the University of Utah as one of the first members of the Huntsman
Cancer Institute. His lab is funded by grants from the National Institutes
of Health and the American Cancer Society. He has been a Scholar of both
the American Cancer Society and the Leukemia and Lymphoma Society
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KEVIN BREEN
Lab Technician
kevin.breen@hci.utah.edu
Kevin received three Bachelors degrees from the University of Idaho in
Microbiology, Molecular Biology/Biochemistry and Philosophy in 2003. He
joined the Ayer lab in the 2003. Kevin’s research in the lab focuses
on the role of MondoA in many diverse cellular processes. Currently, he
is studying a protective role for MondoA in UV induced apoptosis.
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MOHAN KAADIGE, PhD
Post-doctoral fellow
International man of mystery
mohan.kaadige@hci.utah.edu
Mohan received a Masters in Biotechnology in 1997 from Madurai Kamaraj
University, India. He then worked as a junior research fellow at National
Center for Biological Sciences before joining the Ph.D. program at Wayne
State University in 1998. Mohan received his Ph.D. in Molecular Genetics
2003 and joined the Ayer as a post-doctoral fellow. Mohan is part of the
SIN3 group and he is interested in identifying transcriptional targets
that are coregulated by the mSin3A and TLE1 corepressor complexes. His
long-term goal is to unravel how the cooperation between these two abundant
corepressors is regulated.
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CHRIS PETERSON
Graduate Student
chris.peterson@hci.utah.edu
Chris received his Bachelor's degree in environmental science and engineering
from the University of North Carolina at Chapel Hill in 2002 and entered
the Molecular Biology Program at Utah the same year. His work centers
on the use of RNA interference to understand the structure and function
of the mSin3A corepressor complex.
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CARRIE STOLTZMAN, PhD
Senior Research Specialist
carrie.stoltzman@hci.utah.edu
Carrie received her bachelor's degree in Biology from Gustavus Adolphus
College (St. Peter, MN) in 1990, and her Ph.D. in Biological Sciences
from the University of Iowa in 1998. She received a Fellowship in Oncology
from the Serono Foundation to conduct post-doctoral research in the lab
of Dr. Eli Adashi at the University of Utah. She joined the Ayer lab in
2002 and has been involved in various projects associated with the lab's
investigation of the MondoA protein.
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PANKAJ PANDEV
Post Doctoral Fellow
pankaj.pandev@hci.utah.edu
Pankaj received his Masters degree in 1996 and Ph.D. in 2003 from Banaras Hindu University, India in Biochemistry. He worked as post-doc at The Vanderbilt University before joining the Ayer group as post-doctoral fellow. He is studying the properties of conserved regions of MondoA and their role in regulating its activity of the protein.
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ELIZABETH SLOAN
Graduate Student
elizabeth.sloan@hci.utah.edu
Elizabeth graduated from Pacific Lutheran University in 2007 with a B.S. in Biology and Chemistry. She entered the Molecular Biology Program fall of the same year and joined the Ayer Lab in May of 2008. Her research focuses on the role of MondoA in regulating glucose homeostasis. When not in lab she enjoys hiking and skiing in the mountains outside Salt Lake.
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SADHAASIYAM KAMALANAADHAN
Graduate Research Assistant
sadhaasivam.kamalanaadhan@hci.utah.edu
Kamal graduated with a Bachelor's degree in Industrial Biotechnology under Anna University, India in 2007. He is currently pursuing his Masters degree in Biotechnology at the University of Utah. Kamal joined the Ayer lab in 2007 as a research assistant and helps with all the activities related to the day to day functioning of the lab. He is currently researching the induction and repression of MondoA activity by various molecules in different cell lines.
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KYOUNG SIM HAN
Graduate Student
kyoung-sim.han@hci.utah.edu
Kyoung-Sim Han received a Bachelor and a Master degree in Biotechnology from Yonsei University, Korea in 2002 and in 2004. After working as a researcher in a bio-venture company in Korea for 3 years, she entered the Molecular Biology Program at Utah in 2007. Her research focuses on the MondoA function regulated by Myc and the regulation of TXNIP through AMPK-mTOR pathway.
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MICHAEL SIGHINOLFI
Lab Technician
michael.sighinolfi@hci.utah.edu
Michael graduated from Bowdoin College in 2007 with a B.A. in Economics and Chemistry. He joined the Ayer Lab in September of the same year. His research in the lab is focused on MondoA’s function in vivo using a mouse model. He is attempting to create a conditional knockout system to study MondoA’s function in both developing and adult mice. In his spare time, Michael enjoys skiing, hiking, and swimming.
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MARC ELGORT
Graduate Student
marc.elgort@hci.utah.edu
sign: taurus
turn ons: understanding how mondoA is involved in reprogramming cellular metabolism and nutrient utilization during cell growth through its transcriptional regulation of txnip; long walks on the beach; movies with molly ringwald
turn offs: writing blurbs, mean people, the color yellow
education: UCSD 1987 ba biochemistry and cell biology
joined ayer lab: summer 2007
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